Obviously they do not wish to know about your grandmother, your issues or all of the hardships in your life. You need to focus on elements about your life that can illustrate you skill to do the job. Focus on your schooling, your management positions and your achievements after which tell it in a congruent story that it upbeat and fascinating.
There you might be, you walk into the room or workplace that the interview is going to happen. You walk over to the interviewer they usually hold out their hand. The kind of handshake you give goes to say rather a lot about you. Not everyone who interviews you will pick up on it, after all, but many individuals who interview others learn to choose up on delicate alerts like hand-shakes.